PrPC - a Biomarker for Traumatic Brain Injury

Soluble cellular prion protein (PrPC) is a blood-based biomarker for traumatic brain injury (TBI). Researchers at the University of Saskatchewan identified PrPC as a blood-based biomarker corresponding to TBI severity (mild concussion to severe TBI) in sophisticated models provided by the Canadian National Department of Defense. Additional clinical studies confirmed the potential of PrPC as a TBI biomarker (UofS Husky athletics, Banyan Biomarkers). PrPC in blood plasma is measured through an ELISA test developed by the UofS researchers. Clinical validation of this TBI biomarker is ongoing through a collaboration with the Centre for Drug Research and Development in Vancouver, Canada